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c/retatrutide·submitted 1 year ago by u/yannick_salinas

3 months in and triple agonist is still the thing I get wrong

Trial Databranch of 7 comments

Reporting in. 3 months in and triple agonist is still the thing I get wrong. The numbers the title promised, since a headline without them is worthless: 3 months. Everything below is context for those. Stopped at a low step because there was no reason to go further and no data to tell me what further would do. Where…

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7 comments, started 1 year ago
u/incretin_ivyMOD1.4k points·1 year ago

Standing reminder in every thread here: unapproved compound, research material is not for human use, nothing on this board is medical advice.

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u/yannick_salinasOP787 points·1 year ago·edited

Is that the 48-week figure or an earlier readout?

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u/naomi_erdogan-36 points·1 year ago

the escalation is where most of the reported trouble sits

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u/vito_beaulieu1 point·1 year ago

small trial, big effect, wide error bars

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u/rekha_vestergaard293 points·1 year ago

This. The phase 2 result was genuinely large and it was also 48 weeks in a few hundred people.

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[deleted]552 points·1 year ago

[deleted]

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u/blunt_coldbox_2024789 points·1 year ago

Standing reminder in every thread here: unapproved compound, research material is not for human use, nothing on this board is medical advice.

This is the sentence the rest of the board should read first. Phase 2 is not a label.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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