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why does nobody talk about reconstitution

PSA Cold Box ×9 Slow Clap ×2 Clean Column ×2

why does nobody talk about reconstitution. Searched first, found three threads that contradict each other, hence the post.

Wrote the date on the vial as well as the concentration after losing track of which one was opened first.

Shook the first vial because nobody told me not to. It was fine, but I have swirled every one since.

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

I will update this if the picture changes rather than quietly leaving it up.

3,487 up / 823 down81% upvoted15 commentsid lp8jes13 Sep 2024

15 comments

12 in this archive, depth 3

best — the order this archive was captured in

u/katrin_marchetti512 points·1 year ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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u/units_not_mgMOD319 points·1 year ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

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u/katrin_marchettiOP177 points·1 year ago

Are you accounting for the powder volume, or is that where the confusion is?

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u/rosa_mensah265 points·1 year ago

This. Showing the working is the fastest way for somebody else to spot the mistake.

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u/emil_wojcik237 points·1 year ago

Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.

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u/zaid_balogun-26 points·1 year ago

What is written on the vial right now?

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u/sofia_danquah1 point·1 year ago

I would not round that figure. At 5mg/mL a rounding error of two units is a real fraction of the intended amount.

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u/elin_ferrari107 points·1 year ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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u/sigrid_kaufmann60 points·1 year ago

Is that a U-100 syringe? The barrel markings change the answer completely.

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u/liv_nkemelu22 points·1 year ago

Pushback on the syringe advice: a U-100 barrel reads units of volume. Calling them "doses" is how the confusion starts.

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u/units_not_mgsyringe math34 points·1 year ago

The arithmetic in full: concentration is mass over volume, so 30mg into 3mL gives 10mg/mL. A U-100 syringe is graduated at 100 units per millilitre, so 5mg is 5 divided by 10 millilitres, which is 50 units.

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u/bac_water_banditreconstitution21 points·1 year ago

Correction: that gives 100 units, not what you have written. 5mg into 2mL is 2.5mg/mL and the division follows from there.

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