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c/reconstitution·submitted 2 years ago by u/gradient_goblin

insulin syringe is the most under-discussed thing on this board

Discussionbranch of 14 comments

insulin syringe is the most under-discussed thing on this board. Making the case below, and I expect to lose some of it in the comments. Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative. Adding…

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14 comments, started 2 years ago
u/alcohol_aversion102 points·2 years ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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u/aurel_boateng61 points·2 years ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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u/arne_restrepo78 points·2 years ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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u/elodie_grimaldi92 points·2 years ago

Spent 20 weeks confused about this until somebody drew the table for me. 20mg, 1mL, 20mg/mL, 2mg is 10 units. That is the whole thing.

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u/quiet_reader_9928 points·2 years ago

if the maths gives you a fraction of a unit, change the concentration

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u/britta_nakamura35 points·2 years ago

label the vial with the date as well as the concentration

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u/sleep_apnea_sam23 points·2 years ago

Correction: that gives 20 units, not what you have written. 5mg into 1mL is 5mg/mL and the division follows from there.

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u/yusuf_nakamura27 points·2 years ago

I would not round that figure. At 1.67mg/mL a rounding error of two units is a real fraction of the intended amount.

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u/zaid_balogun19 points·2 years ago

Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.

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u/a1c_arcT2D27 points·2 years ago

This. Showing the working is the fastest way for somebody else to spot the mistake.

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u/india_generic_g54 points·2 years ago

Not quite. Bacteriostatic and sterile water are not interchangeable for a multi-draw vial, and the difference is the preservative.

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u/janek_ferrari15 points·2 years ago

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.

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u/gradient_goblinOP61 points·2 years ago

Is that a U-100 syringe? The barrel markings change the answer completely.

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u/freya_onwuka13 points·2 years ago

dead space in the needle hub is real and it is small

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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