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c/reconstitution·posted 7 days ago by u/tl_dr_tina

[Correction] the concentration table going round is off by a factor of ten

Correction Cold Box ×1

the concentration table going round is off by a factor of ten, written plainly and without the jargon that usually swallows this topic.

The lyophilised cake displaces a small volume, so the true concentration is very slightly lower than the arithmetic suggests. It is a fraction of a percent and it is dwarfed by fill tolerance.

The arithmetic in full: concentration is mass over volume, so 20mg into 2mL gives 10mg/mL. A U-100 syringe is graduated at 100 units per millilitre, so 2.5mg is 2.5 divided by 10 millilitres, which is 25 units.

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.

Not medical advice, obviously, and nothing here is approved for human use. One person with a spreadsheet.

570 up / 170 down77% upvoted13 commentsid j7nxk822 Jul 2026

13 comments

5 in this archive, depth 2

best — the order this archive was captured in

u/bac_water_banditMOD60 points·6 days ago

Left up and flaired Explainer — the numbers in this one check out.

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u/vito_beaulieu21 points·6 days ago

write the concentration on the vial in marker, that is the whole post

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u/yusuf_nakamura40 points·6 days ago·edited

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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u/ruben_cabrera22 points·6 days ago

Did the maths give you a whole number of units, or a fraction?

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u/runa_grimaldi25 points·6 days ago·edited

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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