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c/reconstitution·submitted 10 days ago by u/sigrid_kaufmann

[Math] someone check my arithmetic before i draw this up

Mathbranch of 6 comments

Thinking out loud about this: someone check my arithmetic before i draw this up. The failure modes I have actually seen posted here, in order of frequency. One: reconstituting at a different volume than intended and not writing it down, so the next draw is based on a remembered concentration. Two: treating units as a…

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6 comments, started 8 days ago
u/cesar_ivaturi48 points·8 days ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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u/ismael_nwosu0 points·8 days ago

Did the maths give you a whole number of units, or a fraction?

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u/yusuf_nakamura1 point·7 days ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/sigrid_kaufmannOP1 point·8 days ago

That is sterile water, not bacteriostatic. Same appearance, different product, and it matters for a multi-draw vial.

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u/andres_sorensen1 point·7 days ago

label the vial with the date as well as the concentration

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u/reflux_report1 point·8 days ago

Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful.

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The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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