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c/reconstitution·submitted 14 days ago by u/sleep_apnea_sam

cloudy after reconstitution — discard, right? right.

Correctionbranch of 10 comments

cloudy after reconstitution — discard, right? right. Not a hot take, just something I have not seen said plainly here. Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship. Why "more…

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10 comments, started 13 days ago
u/dexa_twice_yearlybody comp161 points·13 days ago

the number you write down is the number you will trust at 6am

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u/oskar_ibarra67 points·13 days ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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u/ilias_cabrera17 points·12 days ago

Agreed — units are volume. Once that lands, the rest of the arithmetic is one division.

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u/hub_opssite staff5 points·12 days ago

more water is not more drug, it is the same drug in a bigger volume

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u/ines_ekstrom9 points·12 days ago

20mg into 2mL is 10mg/mL, and 1mg of that is 10 units

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u/julia_erdogan28 points·12 days ago

do the arithmetic before you reconstitute, not while holding a syringe

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u/sock_puppet_spotter20 points·12 days ago

That is sterile water, not bacteriostatic. Same appearance, different product, and it matters for a multi-draw vial.

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u/sleep_apnea_samOP-15 points·12 days ago

Is that a U-100 syringe? The barrel markings change the answer completely.

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u/santiago_ndiaye1 point·12 days ago

the powder cake sits at the bottom, the volume you add is the volume that counts

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u/niels_roos1 point·12 days ago

What is written on the vial right now?

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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