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c/reconstitution·submitted 1 months ago by u/adaeze_cabrera

someone explain concentration to me like I have not read a paper in years

Explainerbranch of 8 comments

Asking properly rather than in a comment on somebody else’s thread: someone explain concentration to me like I have not read a paper in years. Shook the first vial because nobody told me not to. It was fine, but I have swirled every one since. Wrote the date on the vial as well as the concentration after losing track…

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8 comments, started 1 months ago
u/yusuf_achebe149 points·1 months ago

What concentration did you actually reconstitute at, rather than what did you intend to?

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u/clara_weiss43 points·1 months ago

units are a volume on a U-100 syringe, not a dose

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u/units_not_mgsyringe math27 points·1 months ago

the powder cake sits at the bottom, the volume you add is the volume that counts

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u/tuva_kirchner16 points·1 months ago

aim the stream at the glass wall, not at the cake

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u/oskar_kaufmann21 points·1 months ago

units are a volume on a U-100 syringe, not a dose

Right, and the arithmetic behind it: 5mg in 1mL is 5mg/mL, so 1.5mg is 30 units.

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u/hedda_ekstrom17 points·1 months ago

label the vial with the date as well as the concentration

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u/ismael_nwosu7 points·1 months ago

bacteriostatic water has the preservative, sterile water does not

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u/adaeze_cabrera3 points·1 months ago

reconstituting at a round concentration makes every later dose easy

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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