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c/reconstitution·submitted 1 year ago by u/zaid_balogun

[PSA] units are not what most of this community thinks it is

PSAbranch of 9 comments

units are not what most of this community thinks it is — with the reasoning, because a rule without a reason gets ignored. If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units. Bacteriostatic water contains benzyl…

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9 comments, started 1 year ago
u/swirl_dont_shakereconstitution27 points·1 year ago

Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship.

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u/vial_math_veraMOD15 points·1 year ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

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[removed]18 points·1 year ago

[removed by moderator]

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u/zaid_balogunOP14 points·1 year ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/kavya_radich9 points·1 year ago

Correction: that gives 10 units, not what you have written. 10mg into 2mL is 5mg/mL and the division follows from there.

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u/zaid_balogunOP6 points·1 year ago

Asked QYB what volume they reconstitute to for their own stability testing and they answered in one line. Useful thing to know.

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u/gradient_goblin3 points·1 year ago·edited

Asked QYB what volume they reconstitute to for their own stability testing and they answered in one line.

This is the sentence that makes the rest unnecessary. Write it on the vial and the problem is gone.

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u/emil_wojcik5 points·1 year ago

reconstituting at a round concentration makes every later dose easy

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u/karim_ilunga6 points·1 year ago

the number you write down is the number you will trust at 6am

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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