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c/reconstitution·submitted 1 months ago by u/elodie_grimaldi

[Discussion] the bacteriostatic water advice in here is 3 years out of date

Discussionbranch of 7 comments

the bacteriostatic water advice in here is 3 years out of date. Not a hot take, just something I have not seen said plainly here. The numbers the title promised, since a headline without them is worthless: 3 years. Everything below is context for those. Aim the stream down the wall of the vial rather than into the…

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7 comments, started 1 months ago
u/adaeze_cabrera44 points·1 months ago

Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship.

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u/piotr_bruun27 points·1 months ago

Asked GGPeps what volume they reconstitute to for their own stability testing and they answered in one line. Useful thing to know.

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u/rasmus_kuipers15 points·1 months ago

Cosigning the round-number approach. Reconstituting to something awkward is how you end up drawing 27.5 units at six in the morning.

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u/ines_lindqvist6 points·1 months ago

Same. I got this wrong once, caught it because the units looked absurd, and have written on every vial since.

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u/honest_syringe_20259 points·1 months ago

the number you write down is the number you will trust at 6am

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u/elin_ferrari5 points·1 months ago

Correction: that gives 50 units, not what you have written. 30mg into 3mL is 10mg/mL and the division follows from there.

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u/saskia_rahimi5 points·1 months ago

swirl, never shake

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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