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c/glp1women·posted 7 months ago by u/step_therapy_s

small win: contraception stopped being a problem at week 41

Question

small win: contraception stopped being a problem at week 41. Numbers below. Ask me the boring questions, they are the useful ones.

The hair shedding was the thing that frightened me most and the thing that mattered least. It stopped.

The one practical change that makes this board’s hardest questions tractable: annotate your log with the cycle.

Hormonal variation affects appetite, fluid and symptom intensity in its own right. Without the annotation, a log shows a dose, a week and a set of symptoms that appear to move at random. With it, patterns that were invisible become obvious in about three months.

Members here who have done it consistently report the same thing: the same dose feels genuinely different at different points, and knowing that in advance converts a confusing fortnight into an expected one. It also makes a much better document to bring to an appointment.

I will update this if the picture changes rather than quietly leaving it up.

223 up / 307 down42% upvoted13 commentsid 9e3pv131 Dec 2025

13 comments

13 in this archive, depth 4

best — the order this archive was captured in

u/honest_syringe-4 points·7 months ago

Trial populations for the major programmes were not designed around the questions this board asks most often, which is why the evidence base here is genuinely thinner rather than merely harder to find.

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u/bastian_eriksen1 point·7 months ago

Telogen shedding follows a period of significant weight change rather than a specific compound, and it resolves.

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u/wholesome_lurker6 points·6 months ago·edited

Disagree — that is a general claim about absorption and the specific question needs a pharmacist rather than a board.

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u/step_therapy_s4 points·6 months ago

The questions that leave this board, and where they go.

Anything about pregnancy, planning a pregnancy, or contraception efficacy goes to a clinician. Absorption questions about a specific oral product go to a pharmacist, who can look it up in minutes. Fertility changes with weight loss are well described and worth raising with whoever prescribes, in advance rather than afterwards.

What stays here usefully: experience, cycle-annotated patterns, the vocabulary, and the collective knowledge that a research gap exists. That is a genuinely valuable set of things and it is a smaller set than people arriving here expect. Nothing on this board is medical advice and on this board that is not a formality.

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u/pavel_nkemelu4 points·6 months ago

Asked a pharmacist about the absorption question rather than the internet. Ten minutes, clear answer, done.

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u/blunt_coldbox293 points·6 months ago

PCOS and insulin resistance are the thread that runs through this board

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u/sanne_novak3 points·6 months ago

Went looking for trial data on the specific question asked here and found the population had not been enrolled.

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u/bastian_moreau1 point·6 months ago

That trial did not enrol the population you are asking about, so it cannot answer this.

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u/aleksi_grimaldi1 point·6 months ago

Are you asking about the compound, the weight loss, or both?

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u/low_appetite_lisa1 point·6 months ago·edited

That is a general statement about gastric emptying, and the question was about a specific product.

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u/neha_rahimi1 point·6 months ago

Small fix — insulin resistance is a feature commonly seen in PCOS, not a synonym for it.

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u/forest_plot_fionastats1 point·6 months ago

Fertility changed faster than I expected with the weight loss. Nobody had raised it and I wish somebody had.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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