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c/glp1women·posted 3 months ago by u/vito_beaulieu

reading cycle threads from 2024 and half of it aged badly

PCOS

reading cycle threads from 2024 and half of it aged badly. I have gone back and forth on this for months.

Fertility changed faster than I expected with the weight loss. Nobody had raised it and I wish somebody had.

Anything involving pregnancy, contraception efficacy or fertility planning belongs with a clinician. That is not a disclaimer, it is where the answers actually are.

Started logging the cycle in the same sheet as the dose. Three months later the pattern was obvious and it had been invisible before.

Sceptical readings welcome. The confident ones are the ones I distrust.

81 up / 3 down97% upvoted13 commentsid 1mhzxs18 Apr 2026

13 comments

13 in this archive, depth 6

best — the order this archive was captured in

u/sanne_novak15 points·3 months ago

Questions about oral contraceptive absorption and gastric emptying are legitimate pharmacology questions with product-specific answers. A pharmacist can answer them properly; a board cannot.

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u/vito_beaulieuOP11 points·3 months ago

The same dose genuinely feels different at different points in the month for me. Took a year to notice and it was in the log the whole time.

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u/tired_ledger_ftw4 points·3 months ago

Same. Perimenopause overlapping with all of this is the least documented area on the whole site.

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u/rina_sobczak3 points·3 months ago

hair shedding follows the rate of loss, not the compound

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u/viktor_erdogan3 points·3 months ago

Have you asked a pharmacist about the absorption question specifically?

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u/vito_beaulieuOP2 points·3 months ago·edited

The hair shedding was the thing that frightened me most and the thing that mattered least. It stopped.

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u/vito_beaulieuOP2 points·3 months ago

How many cycles has the pattern held for?

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u/karim_restrepo2 points·3 months ago

symptom patterns can track the cycle rather than the dose

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u/elin_lindqvist1 point·3 months ago·edited

Telogen shedding follows a period of significant weight change rather than a specific compound, and it resolves.

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u/yusuf_ramos7 points·3 months ago

Cosigning on fertility changing with weight loss. It catches people who were not expecting it at all.

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u/gustav_lindholm10 points·3 months ago

Insulin resistance is a common feature in PCOS, which is why the metabolic conversation overlaps so heavily with this board. A diagnosis and a finding are still different things and the distinction matters for what the evidence says.

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u/signe_villalobos3 points·3 months ago

Asked a pharmacist about the absorption question rather than the internet. Ten minutes, clear answer, done.

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u/viktor_erdogan1 point·3 months ago

Perimenopause and all of this at once, and there is essentially nothing written about the combination anywhere.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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