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c/glp1women·posted 2 months ago by u/aleksi_grimaldi

stalled for 15 weeks at 2.5mg and I refuse to panic this time

Caution Long Haul ×4

stalled for 15 weeks at 2.5mg and I refuse to panic this time. It is the sort of thing everyone half-believes and nobody writes down.

The numbers the title promised, since a headline without them is worthless: 15 weeks and 2.5mg. Everything below is context for those.

Questions about oral contraceptive absorption and gastric emptying are legitimate pharmacology questions with product-specific answers. A pharmacist can answer them properly; a board cannot.

Fertility can change with weight loss and improved insulin sensitivity. That is a well-described phenomenon and worth knowing about in advance rather than discovering.

I will update this if the picture changes rather than quietly leaving it up.

2,618 up / 2,330 down53% upvoted20 commentsid 16yj4628 May 2026

20 comments

18 in this archive, depth 5

best — the order this archive was captured in

u/emil_marchand-36 points·2 months ago

Anything involving pregnancy, contraception efficacy or fertility planning belongs with a clinician. That is not a disclaimer, it is where the answers actually are.

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u/aleksi_grimaldiOP1 point·2 months ago·edited

Perimenopausal, or is that a separate question?

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u/elin_lindqvist1 point·2 months ago

How many cycles has the pattern held for?

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u/karim_restrepo1 point·2 months ago

nothing on this board is a substitute for someone who knows your history

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u/aleksi_grimaldiOP1 point·1 months ago

Have you asked a pharmacist about the absorption question specifically?

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u/aleksi_grimaldiOP1 point·1 months ago

Correction: that trial did not enrol the population being discussed, so it cannot support the claim.

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u/low_appetite_lisa1 point·1 months ago

perimenopause and this overlap in ways nobody has good data on

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[removed]1 point·2 months ago

[removed by moderator]

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u/vito_beaulieu1 point·2 months ago

fertility can change with weight loss and that surprises people

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u/santiago_marchetti1 point·1 months ago

I would not read one person’s cycle-linked experience as a general pattern. The variation here is enormous.

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u/sena_teixeira1 point·1 months ago

PCOS is a diagnosis, not a description, and it matters which you mean

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u/sulphur_burps_sue1 point·2 months ago

fertility can change with weight loss and that surprises people

Agreed, and the research gap being real rather than imagined is worth saying out loud.

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u/ferran_laurent1 point·2 months ago

Small fix — insulin resistance is a feature commonly seen in PCOS, not a synonym for it.

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u/joaquin_trevino1 point·1 months ago

the trials were not designed to answer most of the questions asked here

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u/rasmus_petrescu1 point·1 months ago

The same dose genuinely feels different at different points in the month for me. Took a year to notice and it was in the log the whole time.

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u/ilias_kaufmann1 point·2 months ago

cycle timing changes how the same week feels

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u/jarno_karlsen1 point·2 months ago

hair shedding follows the rate of loss, not the compound

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u/bastian_aalto1 point·1 months ago

Same. Perimenopause overlapping with all of this is the least documented area on the whole site.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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