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c/coldchain·submitted 1 months ago by u/andres_restrepo

light exposure matters more for some compounds than others and nobody tabulates it

Questionbranch of 7 comments

Posting this as a discussion rather than a claim: light exposure matters more for some compounds than others and nobody tabulates it. A transit temperature logger records a distribution, and time above a threshold matters as much as peak temperature. That is the argument for logging rather than guessing. Gel packs…

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7 comments, started 1 months ago
u/bence_ibarra47 points·1 months ago

Regional stock changes the question rather than answering it: shorter lanes mean less exposure and fewer variables, which is why the warehouse question is worth asking before ordering in summer.

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u/niels_yilmaz22 points·29 days ago

That is the ambient temperature at the destination, not the temperature inside the box. The logger measures the second one.

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u/bruno_dumitru15 points·29 days ago

That is the ambient temperature at the destination, not the temperature inside the box.

This is the distinction that resolves most threads here — powder and solution are different problems.

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u/osman_brandt4 points·29 days ago

Cosigning the regional stock point. Ordering from a warehouse in the UK took the whole question off my table.

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u/andres_restrepoOP9 points·29 days ago

Powder or already in solution?

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u/milos_vestergaard3 points·29 days ago

Once in solution, the relevant risks are hydrolysis, aggregation and, for some sequences, oxidation. Refrigeration slows all three; freezing a solution introduces a separate risk at the ice interface.

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u/certified_referenceQC17 points·29 days ago·edited

That is the ambient temperature at the destination, not the temperature inside the box.

Disagreeing with this line only: freezing a reconstituted vial is not a safe default.

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