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c/coa·submitted 1 year ago by u/valeria_karlsen

[Discussion] the purity advice in here is 3 years out of date

Discussionbranch of 11 comments

the purity advice in here is 3 years out of date. It is the sort of thing everyone half-believes and nobody writes down. Hard numbers: 3 years. Anything softer than that is flagged as an impression. My first certificate had a compound name, a percentage and a logo. I thought that was normal. It is not, and now I know…

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11 comments, started 1 year ago
u/cormac_pereira291 points·1 year ago

Area percent is the peak area of your compound over the total integrated area, at one wavelength, on one gradient. It is a relative measure of what the detector saw, not a mass fraction of the vial.

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[removed]206 points·1 year ago

[removed by moderator]

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u/purity_pedantanalytical87 points·1 year ago

The PDF creation date being later than the analysis date is usually a re-issue or a re-export. It is worth one question and it is not evidence of anything on its own.

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u/step_therapy_s46 points·1 year ago

a certificate with no method line is decorative

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u/certified_referenceQC198 points·1 year ago

Ask what the stability statement was written against — temperature, light, and whether it was the lyophilised powder or the reconstituted solution. Those are three different claims.

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u/camila_lindqvist97 points·1 year ago

I would not read a rounded figure as evasive. Plenty of documents round to one decimal as house style.

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u/alcohol_aversion29 points·1 year ago

water content is on there and everyone skips it

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u/valeria_karlsenOP157 points·1 year ago

axis labels included, always

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u/clara_restrepo127 points·1 year ago

Did you ask for the batch-specific document, or is this the catalogue one?

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u/dario_boateng72 points·1 year ago

Same view. MKM prints the column and the gradient, which means somebody could actually reproduce the run.

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u/santiago_szabo28 points·1 year ago

batch number, date of analysis, method, individual impurities — that is the minimum set

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