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c/coa·posted 4 months ago by u/vito_chowdhury

[Lab] QSC BPC — Janoshik came back 98.7% against a claimed 98.5%

Lab

Posting this because the title is the whole finding — QSC BPC — Janoshik came back 98.7% against a claimed 98.5% — and a number without its method is a rumour.

98.7% and 98.5% — those are the numbers, and they are the ones I am willing to defend.

Started keeping a folder of every certificate I have been sent. The ones that itemise impurities are a small group and they are mostly the same suppliers.

Asked for the storage condition behind the stability statement. Got it in a sentence. It is a two-line email and almost nobody sends it.

Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.

78 up / 104 down43% upvoted13 commentsid ybdamm21 Mar 2026
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13 comments

13 in this archive, depth 4

best — the order this archive was captured in

u/certified_referenceMOD11 points·4 months ago

Left up and flaired Explainer. This is the answer we keep linking, written properly.

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u/andres_restrepo-22 points·4 months ago

redact your own name, never the batch details

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u/vito_chowdhuryOP1 point·4 months ago

That is the catalogue certificate rather than the batch-specific one. Same layout, completely different status.

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u/laila_yilmaz1 point·4 months ago

Small fix — 214nm, not 280nm. It matters here because the impurity you are asking about barely absorbs at the longer wavelength.

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u/valeria_karlsen6 points·4 months ago

Batch number and date of analysis, are both on there?

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[removed]7 points·4 months ago

[removed by moderator]

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u/neha_erdogan3 points·4 months ago

net peptide content and purity are two different numbers on the same vial

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u/honest_syringe244 points·4 months ago

the lot on the vial has to match the lot on the page

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u/yannick_haddad3 points·4 months ago

That is not what the method line says. It names the technique; it does not certify the operator.

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u/vito_chowdhuryOP5 points·4 months ago

My first certificate had a compound name, a percentage and a logo. I thought that was normal. It is not, and now I know what to ask for.

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u/cormac_pereira7 points·4 months ago

UV at 214nm sees the peptide bond and picks up almost everything; at 280nm you are looking at aromatics only. Which wavelength the number came from is part of the number.

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u/freya_baptista4 points·4 months ago

Careful — "the metadata looks odd" is a reason to ask a question, not a conclusion. Re-issues are ordinary.

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u/yannick_haddad1 point·4 months ago

water content is on there and everyone skips it

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

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Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

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