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c/coa·submitted 2 years ago by u/reflux_report

[Discussion] can we stop arguing about batch until somebody posts a number

Discussionbranch of 7 comments

Question in the title, detail here: can we stop arguing about batch until somebody posts a number. Area percent is the peak area of your compound over the total integrated area, at one wavelength, on one gradient. It is a relative measure of what the detector saw, not a mass fraction of the vial. UV at 214nm sees the…

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7 comments, started 2 years ago
u/gastric_emptying_g64 points·2 years ago

Did you ask for the batch-specific document, or is this the catalogue one?

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u/karma_irrelevant20 points·2 years ago

redact your own name, never the batch details

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u/reflux_reportOP16 points·2 years ago

chromatogram or it did not happen

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u/reflux_reportOP12 points·2 years ago

Small fix — 214nm, not 280nm. It matters here because the impurity you are asking about barely absorbs at the longer wavelength.

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u/clara_restrepo12 points·2 years ago

That is not what the method line says. It names the technique; it does not certify the operator.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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