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c/coa·submitted 1 year ago by u/first_hundred

[Lab] split one vial across VendorInvestigate and PeptideMeter — 97.2% and 98.4%

Labbranch of 8 comments

The claim in the title is exactly the claim I am making: split one vial across VendorInvestigate and PeptideMeter — 97.2% and 98.4%. Nothing implied beyond it. Pulling the figures out of the title: 97.2% and 98.4%. All of it is written down as it happened rather than reconstructed. The four things a certificate must…

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8 comments, started 1 year ago
u/zeynep_zielinski-9 points·1 year ago

What does the method line actually say? Not the technique — the column and the gradient.

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u/gastric_emptying_g-13 points·1 year ago

batch number, date of analysis, method, individual impurities — that is the minimum set

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u/honest_syringe241 point·1 year ago

batch number, date of analysis, method, individual impurities — that is the minimum set

gastric_emptying_g has the distinction right — one is a fraction of the detector signal, the other is a fraction of the mass.

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u/ismael_eriksen0 points·1 year ago

gastric_emptying_g has the distinction right — one is a fraction of the detector signal, the other is a fraction of the mass.

This is the sentence to take away. The rest of the thread is footnotes to it.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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