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c/bpc157·posted 1 year ago by u/piotr_grimaldi

sequence: what the trials say vs what this community says

Lab Clean Column ×2 Long Haul ×1

sequence: what the trials say vs what this community says. Not a hot take, just something I have not seen said plainly here.

Paid for identity confirmation rather than just purity for the first time here. Worth it, and it is not the default on most certificates.

Regulatory classification differs between jurisdictions and has changed in several of them recently. Any answer to a status question needs a place and a date attached.

Research-use-only material is not approved for human use. In this board that is not a formality — it is the reason the clinical evidence base is as thin as it is.

Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.

1,864 up / 347 down84% upvoted16 commentsid 1w088n19 Oct 2024

16 comments

13 in this archive, depth 4

best — the order this archive was captured in

u/kavya_verhoeven0 points·1 year ago

It is a fifteen-residue peptide with a published sequence, which makes synthesis straightforward and makes identity verification the meaningful test rather than an optional extra.

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u/honest_syringe175 points·1 year ago·edited

Bought small, tested identity first, and only then thought about anything else. That order felt right.

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u/pavel_kravchenko205 points·1 year ago

That claim traces back to a single preclinical paper that says something considerably narrower.

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u/elin_varga137 points·1 year ago

Push back: "no reported harms" in a literature with almost no human trials is not a safety finding.

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u/ayesha_erdogan72 points·1 year ago

Asked QST for the theoretical mass alongside the certificate and they sent it without asking why.

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u/piotr_grimaldiOP130 points·1 year ago

That claim traces back to a single preclinical paper that says something considerably narrower.

Agreed — and the preclinical to clinical gap is where nearly all the overclaiming happens.

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[deleted]47 points·1 year ago

[deleted]

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u/curious_panel_only132 points·1 year ago

preclinical enthusiasm is not clinical evidence

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u/piotr_grimaldiOP71 points·1 year ago·edited

Has anyone posted an independent result on that batch?

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u/batch_number_bertievetting0 points·1 year ago

Has anyone posted an independent result on that batch?

piotr_grimaldi is right that a pure something-else is still something else.

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u/sequence_checkerMOD49 points·1 year ago·edited

Citation requested rather than removal. A claim here should say whether its source is preclinical.

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u/osman_brandt-38 points·1 year ago

Every claim I could trace in this board went back to about four papers. That was a sobering afternoon.

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u/tired_ledger_ftw1 point·1 year ago·edited

That is a purity figure, not an identity confirmation. Two different tests and only one answers the question asked.

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About c/bpc157

BPC-157 as it actually is: a pentadecapeptide with a genuinely interesting rodent tendon-and-gut literature, near-zero controlled human data, a naming and sequence mess in the supply chain, and a regulatory status that changed sharply in several countries.

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c/bpc157 rules
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