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c/bpc157·posted 10 days ago by u/nils_ferreira

[Paper] what the rat tendon work actually measured

Paper

what the rat tendon work actually measured. I would rather ask a basic question now than get this wrong quietly for two months.

Paid for identity confirmation rather than just purity for the first time here. Worth it, and it is not the default on most certificates.

Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.

Sent a vial to Medutest: 99.6% against a claimed 99.0%, with the mass confirming the sequence. Both halves mattered to me.

Would rather be corrected in public than confident in private.

44 up / 14 down76% upvoted10 commentsid 1v6c7319 Jul 2026

10 comments

10 in this archive, depth 4

best — the order this archive was captured in

u/pavel_kravchenko-36 points·10 days ago

Regulatory classification differs between jurisdictions and has changed in several of them recently. Any answer to a status question needs a place and a date attached.

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u/enzo_danquah5 points·9 days ago

Bought small, tested identity first, and only then thought about anything else. That order felt right.

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u/curious_panel_only2 points·9 days ago

I would not extrapolate a mechanism from a model system to a person in one step, which is what that comment does.

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u/hplc_hobbyistruns their own column3 points·9 days ago

the human evidence is thin and the rodent evidence is not

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u/piotr_grimaldi1 point·9 days ago

identity, quantity, stability — three separate questions

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u/nils_ferreira2 points·10 days ago

Purity by area percent tells you the sample is homogeneous. Mass spectrometry tells you what the homogeneous thing is. For a short peptide, the second question is the one worth paying for.

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u/nils_ferreiraOP1 point·10 days ago

Kept a reconstituted vial too long out of curiosity and learned something about solution stability I would rather have read.

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u/line_petrov1 point·10 days ago

Small fix — fifteen residues, not seventeen. The sequence is public and easy to check.

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[removed]1 point·10 days ago

[removed by moderator]

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u/honest_syringe2 points·8 days ago

Agreed. Identity is the question here. A short peptide can be synthesised by almost anyone and the sequence is what you are actually buying.

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About c/bpc157

BPC-157 as it actually is: a pentadecapeptide with a genuinely interesting rodent tendon-and-gut literature, near-zero controlled human data, a naming and sequence mess in the supply chain, and a regulatory status that changed sharply in several countries.

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