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c/bpc157·posted 5 months ago by u/mariam_cabrera

[Lab] 12th independent test on SGN — 98.1% on a claimed 98.0%, and the trend is the interesting part

Lab Slow Clap ×5

Result first, context after: 12th independent test on SGN — 98.1% on a claimed 98.0%, and the trend is the interesting part. Everything below is how it was ordered, stored and sent.

Pulling the figures out of the title: 98.1% and 98.0%. All of it is written down as it happened rather than reconstructed.

Every claim I could trace in this board went back to about four papers. That was a sobering afternoon.

Kept a reconstituted vial too long out of curiosity and learned something about solution stability I would rather have read.

Happy to answer the boring questions. Those are usually the ones worth asking.

1,122 up / 294 down79% upvoted33 commentsid 10dt7n4 Feb 2026
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33 comments

19 in this archive, depth 4

best — the order this archive was captured in

u/ruben_cabrera169 points·5 months ago

Research-use-only material is not approved for human use. In this board that is not a formality — it is the reason the clinical evidence base is as thin as it is.

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u/mariam_cabreraOP72 points·5 months ago

Research-use-only material is not approved for human use.

Agreed — and the preclinical to clinical gap is where nearly all the overclaiming happens.

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u/rui_only_roMOD91 points·5 months ago

Left up. It distinguishes rodent work from human work, which is the standard on this board.

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u/marta_ilunga122 points·5 months ago

Assumed regulatory status was static and it was not. Checked again this year and the answer had changed where I live.

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[deleted]45 points·5 months ago

[deleted]

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u/nils_ferreira87 points·5 months ago

Careful. Regulatory status differs by jurisdiction and has changed; a confident global statement is going to be wrong somewhere.

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u/rosa_almeida-24 points·5 months ago

What jurisdiction are you asking about? The answer has changed in several.

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u/tb500_tangent1 point·5 months ago·edited

What jurisdiction are you asking about?

rosa_almeida is right that a pure something-else is still something else.

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u/aurel_boateng1 point·5 months ago

This. Mass spectrometry for identity, not just an area percent, because a pure something-else is still something else.

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u/karim_restrepo1 point·5 months ago

Small fix — fifteen residues, not seventeen. The sequence is public and easy to check.

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u/tomas_kimani1 point·5 months ago

Was there identity confirmation, or only a purity figure?

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u/vikram_mbeki43 points·5 months ago

Agreed — cheap to make is a double-edged fact and it explains a lot about this corner of the market.

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u/mariam_cabreraOP34 points·5 months ago

pentadecapeptide, fifteen residues, and the sequence is public

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u/fatima_wojcik11 points·5 months ago

a fifteen-residue peptide is easy to make and easy to make badly

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u/milos_mensa16 points·5 months ago

Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.

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u/joaquin_ivaturi12 points·5 months ago

regulatory status varies by jurisdiction and it has moved recently

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u/marit_sandvik14 points·5 months ago

ask for the mass spectrum, not just the purity number

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u/honest_syringe2430 points·5 months ago

Agreed — cheap to make is a double-edged fact and it explains a lot about this corner of the market.

Disagreeing with this line: that paper is in a rodent model and it is being quoted as a human result.

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About c/bpc157

BPC-157 as it actually is: a pentadecapeptide with a genuinely interesting rodent tendon-and-gut literature, near-zero controlled human data, a naming and sequence mess in the supply chain, and a regulatory status that changed sharply in several countries.

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