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reading SURMOUNT threads from 2024 and half of it aged badly
The title is the argument: reading SURMOUNT threads from 2024 and half of it aged badly. Here is the rest of it. Discontinuation rates are a tolerability result. A…
u/hugo_norgaard
Contributes reviews on supplier material. Based in Ibadan.
member · joined 14 May 2025
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Overview — page 2 of 2
comment on how much of what we believe about beginner actually comes from what is threads in c/newbiequestions · 1 points · 1 year ago
What does the wiki page on this say — genuinely asking, not deflecting?
This is the answer. Everything else in the thread is elaboration on it.
comment on why does nobody talk about maintenance in c/maintenancephase · 13 points · 1 year ago
None of this is a taper plan.
usp_appendix is right that stretching and reducing are different levers. Worth separating in every one of these threads.
comment on three years of long term threads, summarised so you do not have to read them in c/maintenancephase · 1 points · 1 year ago
Small fix — you have described interval stretching and called it a dose reduction. The exposure profiles differ.
comment on reading SURMOUNT threads from 2024 and half of it aged badly in c/trialwatch · 3 points · 1 year ago
Argued for a week about a result and then read the limitations section, which conceded most of my opponent’s point.
comment on [Discussion] the long term advice in here is 3 years out of date in c/maintenancephase · 1 points · 1 year ago
Withdrawal studies in this class consistently show substantial regain after discontinuation. That is a pharmacological finding about a chronic condition, not a statement about anyone’s discipline.
comment on 5 months in and metformin is still the thing I get wrong in c/t2dglp1 · 1 points · 2 years ago
the fasting number is the one people fixate on and it moves last
comment on help me understand basics, I have read the wiki twice in c/newbiequestions · 2 points · 2 years ago
Right, and writing the concentration on the vial is the single best habit anyone here can start with.
Agreed, and for anyone finding this later: that is the normal experience, not a warning sign.
comment on [Results] 19 weeks on 0.25mg, full numbers, ask me anything boring in c/maintenancephase · 15 points · 2 years ago
Disagree with chasing the last stretch by going up. You are trading a real side-effect cost for a number you chose arbitrarily.
comment on my hs-CRP moved and I cannot work out whether dose stretching is why in c/maintenancephase · 231 points · 2 years ago
Withdrawal studies in this class consistently show substantial regain after discontinuation. That is a pharmacological finding about a chronic condition, not a statement about anyone’s discipline.