u/elin_lundgren
Contributes reviews on supplier material. Based in Verona.
member · joined 14 May 2025
Comments — page 2 of 2
comment on how much of what we believe about amylin actually comes from co-agonism threads in c/cagrilintide · 87 points · 1 year ago
Careful — that is a dosing intuition carried over from another board and there is no basis for it here.
comment on [Discussion] we are measuring receptor at the wrong time and calling it noise in c/glp1science · 537 points · 1 year ago
Glucose-dependent insulin secretion is why hypoglycaemia risk is low as monotherapy: the effect scales with glycaemia rather than acting unconditionally.
comment on gallbladder — 15 things I got wrong before I got it right in c/sideeffects · 206 points · 1 year ago
Mine settled at week 56 and has not come back since, across two more steps.
comment on [Discussion] can we stop arguing about fatigue until somebody posts a number in c/sideeffects · 1 points · 2 years ago
Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.
comment on gastric emptying — 12 things I got wrong before I got it right in c/glp1science · 110 points · 2 years ago
GIP receptor biology is genuinely unsettled — there is a live argument about agonism versus antagonism at the receptor — and the clinical results are robust regardless, which is an uncomfortable and interesting position.
comment on [Meta] proposal — a flair for gastric emptying posts in c/glp1science · 128 points · 2 years ago
Disagree. That is a preclinical finding in a rodent model and you are stating it as human pharmacology.
comment on am I the only one who found amylin harder than the injections in c/cagrilintide · 229 points · 2 years ago
Nothing containing this compound is approved as a standalone product, and research-use-only material is not approved for human use.
comment on what changed for me between month 8 and month 12 in c/sideeffects · 15 points · 2 years ago
fibre and water before you buy anything to fix it
comment on week 17 check-in — 4kg down, fatigue manageable, one thing confusing me in c/cagrilintide · 431 points · 2 years ago
Correction: that is the combination programme, not the monotherapy readout. Different arms, different numbers.
comment on does gastric emptying actually matter or is it forum lore at this point in c/glp1science · 151 points · 2 years ago
What was the exposure in that experiment relative to therapeutic?
comment on does gastric emptying actually matter or is it forum lore at this point in c/glp1science · 240 points · 2 years ago
dose response is not linear and nobody should assume it is
comment on tried reflux for 11 weeks. here is what happened. in c/sideeffects · 2 points · 2 years ago
Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.
comment on [Discussion] incretin is doing more work than we give it credit for in c/glp1science · 220 points · 2 years ago
Glucose-dependent insulin secretion is why hypoglycaemia risk is low as monotherapy: the effect scales with glycaemia rather than acting unconditionally.
comment on 17 months in and fatigue is still the thing I get wrong in c/sideeffects · 22 points · 2 years ago
Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.