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MACE-3 is not a weight-loss endpoint and that is precisely why SELECT mattered.

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Comments — page 3 of 3

comment on three years of insulin syringe threads, summarised so you do not have to read them in c/reconstitution · 82 points · 1 year ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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comment on someone explain dead space to me like I have not read a paper in years in c/reconstitution · 21 points · 2 years ago

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.

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comment on Apotheke — 10 things I got wrong before I got it right in c/glp1eu · -11 points · 2 years ago

the reimbursement criteria are published in most member states

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comment on nobody warned me about reflux and I would have liked the warning in c/bloodwork · 70 points · 2 years ago

Have you taken this to whoever ordered it?

Agreed — and standardising the draw conditions is the cheapest improvement available.

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comment on [Question] bacteriostatic water — what am I missing here in c/reconstitution · -37 points · 2 years ago

The failure modes I have actually seen posted here, in order of frequency.

One: reconstituting at a different volume than intended and not writing it down, so the next draw is based on a remembered concentration. Two: treating units as a dose rather than a volume, which breaks the moment the concentration changes. Three: assuming a syringe is U-100 when it is not.

All three are solved by the same two habits — do the arithmetic before the water goes in, and write the result on the glass. Neither costs anything and between them they cover almost every question this board gets.

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comment on [Discussion] can we stop arguing about ApoB until somebody posts a number in c/bloodwork · 122 points · 2 years ago

ask whether the lab changed its assay between your two draws

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comment on does external review actually matter or is it forum lore at this point in c/insurancefights · 154 points · 2 years ago

That criterion is from the previous plan year. The current bulletin has different wording.

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comment on why does nobody talk about units in c/reconstitution · 152 points · 2 years ago

Why "more water" keeps confusing people, including me for a month.

The vial contains a fixed amount of peptide. Water changes nothing about that amount. What it changes is concentration, and concentration is the divisor between the dose you want and the volume you draw.

So doubling the water halves the concentration and doubles the units for the same dose. Nothing is diluted in any sense that matters; you are simply reading a bigger number off the same barrel. Pick the water volume that puts your usual dose on a whole number of units and life gets easier.

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comment on [Meta] proposal — a flair for bacteriostatic water posts in c/reconstitution · 36 points · 2 years ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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comment on how much of what we believe about A1c actually comes from ferritin threads in c/bloodwork · 14 points · 2 years ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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comment on [Question] how do you actually verify insulin syringe in c/reconstitution · 0 points · 2 years ago

This. Showing the working is the fastest way for somebody else to spot the mistake.

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