u/bruno_dumitru
Contributes reviews on supplier material. Based in Angers.
member · joined 14 May 2025
Comments — page 2 of 3
comment on [Meta] the state board rule is doing its job and people should stop complaining in c/compounding · 1 points · 6 months ago
Yes. The shortage list is the legal hinge for the whole arrangement and its status is public.
comment on [Meta] the state board rule is doing its job and people should stop complaining in c/compounding · 135 points · 6 months ago
if a clinic will not name the facility, that is your answer
comment on [Meta] the state board rule is doing its job and people should stop complaining in c/compounding · 307 points · 6 months ago
Who is the prescriber, and are they the same organisation as the pharmacy?
comment on how much of what we believe about gas fees actually comes from confirmations threads in c/cryptopay · 1 points · 6 months ago
A test transaction costs one extra network fee and verifies the address, the network and the recipient’s crediting process before the main amount moves.
comment on mg/mL — 16 things I got wrong before I got it right in c/reconstitution · 33 points · 6 months ago
Correction: that gives 60 units, not what you have written. 10mg into 3mL is 3.33mg/mL and the division follows from there.
comment on the lyophilised question that gets asked weekly, answered properly in c/coldchain · 26 points · 6 months ago
Yes — a logger in the box turns a fortnight of speculation into a chart.
comment on the units thing finally clicked for me and I want to write it down in c/reconstitution · 246 points · 6 months ago
That only works if the fill weight is exactly the label weight, and it usually is not exactly anything.
comment on weight — 23 things I got wrong before I got it right in c/dosinglogs · 30 points · 6 months ago
Contemporaneous records do not drift; reconstructed ones do, and the drift is systematic rather than random because memory smooths.
comment on three years of sequence threads, summarised so you do not have to read them in c/bpc157 · 42 points · 7 months ago
Do you have the mass spectrum?
comment on [Discussion] can we stop arguing about packaging until somebody posts a number in c/coldchain · 14 points · 7 months ago
Regional stock changes the question rather than answering it: shorter lanes mean less exposure and fewer variables, which is why the warehouse question is worth asking before ordering in summer.
comment on [Lab] CPC orfo — Janoshik came back 98.3% against a claimed 97.5% in c/orforglipron · 6 points · 7 months ago
Disagree. You are comparing doses across a small molecule and a peptide, which is not a comparison of anything.
comment on [Question] dead space — what am I missing here in c/reconstitution · 8 points · 7 months ago
What concentration did you actually reconstitute at, rather than what did you intend to?
erez_perrin has the units point exactly right. They are a volume on the barrel and nothing else.
comment on [Discussion] can we stop arguing about chargeback until somebody posts a number in c/cryptopay · 6 points · 8 months ago
The transaction hash is the canonical receipt: it is public, verifiable by either party, and it is what a support query should quote.
comment on the confirmations question that gets asked weekly, answered properly in c/cryptopay · -25 points · 8 months ago
Which network, exactly?
comment on dead space is the most under-discussed thing on this board in c/reconstitution · 33 points · 8 months ago
Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful.
comment on someone explain compounding to me like I have not read a paper in years in c/compounding · 11 points · 8 months ago
compounded is not generic, there is no equivalence claim
comment on reading bacteriostatic water threads from 2024 and half of it aged badly in c/reconstitution · 1k points · 9 months ago
units are a volume on a U-100 syringe, not a dose
comment on is it normal to get muscle cramps at week 86 in c/orforglipron · 6 points · 9 months ago
phase 3 is where the comparison becomes fair
Agreed, and it is why the oral peptide comparison keeps misleading people.
comment on the 503A question that gets asked weekly, answered properly in c/compounding · 148 points · 9 months ago
Compounded preparations are not approved products and carry no bioequivalence claim. That is a statement about regulatory category, not about quality.
comment on weight: the version I wish someone had shown me in week 1 in c/dosinglogs · 58 points · 9 months ago
Same conditions each time for the weigh-in?
comment on [Meta] proposal — a flair for confirmations posts in c/cryptopay · 20 points · 10 months ago
A test transaction costs one extra network fee and verifies the address, the network and the recipient’s crediting process before the main amount move
Disagreeing here: that is a network fee at a busy hour and it is not the supplier’s doing.
comment on [Question] how do you actually verify data logger in c/coldchain · 99 points · 10 months ago
Not convinced. A warm pack on day six is expected behaviour from a pack designed for four.
comment on [Question] how do you actually verify units in c/reconstitution · 180 points · 10 months ago
if the maths gives you a fraction of a unit, change the concentration
comment on reading log threads from 2024 and half of it aged badly in c/dosinglogs · 5 points · 11 months ago
the column you will wish you had is sleep
comment on [Discussion] can we stop arguing about ice pack until somebody posts a number in c/coldchain · 89 points · 1 year ago
Gel packs are designed for a duty cycle. A liquid pack at the end of a longer-than-expected transit is a pack behaving as specified, not evidence of an excursion in the vial.
comment on why does nobody talk about tendon in c/bpc157 · 31 points · 1 year ago
I would not extrapolate a mechanism from a model system to a person in one step, which is what that comment does.
comment on does compounding actually matter or is it forum lore at this point in c/compounding · 1 points · 1 year ago
Not convinced. You are comparing a compounded concentration with a branded one and assuming they match.
comment on why does nobody talk about chargeback in c/cryptopay · 1 points · 1 year ago
A token symbol identifies an asset, not a network. The same symbol commonly exists on several chains with incompatible address formats, and sending across that boundary is generally unrecoverable.
comment on unpopular opinion: most of what gets said here about units are guesswork in c/reconstitution · 72 points · 1 year ago
Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.
comment on tendon: what the trials say vs what this community says in c/bpc157 · 100 points · 1 year ago
Careful. Regulatory status differs by jurisdiction and has changed; a confident global statement is going to be wrong somewhere.
comment on [Discussion] we are measuring data logger at the wrong time and calling it noise in c/coldchain · 21 points · 1 year ago
transit temperature is a distribution, not a number
comment on does pharmacy actually matter or is it forum lore at this point in c/glp1eu · 4 points · 1 year ago
Cosigning on cross-border prescriptions. The rules exist and they are narrower than the summaries suggest.
comment on [Question] Spain — has anyone got a straight answer on 503B in c/compounding · 49 points · 1 year ago
Yes — asking which facility, by name, is the single most useful question and most clinics will answer it.
comment on how much of what we believe about gas fees actually comes from USDC threads in c/cryptopay · 45 points · 1 year ago
Agreed. Network first, address second, amount third, and in that order every time.
comment on three years of regulatory threads, summarised so you do not have to read them in c/bpc157 · 8 points · 1 year ago
Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.
comment on the insulin syringe question that gets asked weekly, answered properly in c/reconstitution · 3 points · 1 year ago
Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful.
comment on how much of what we believe about pharmacy actually comes from EMA threads in c/glp1eu · 1 points · 1 year ago
reimbursement is national, not European, and that is the whole board
comment on how much of what we believe about pharmacy actually comes from EMA threads in c/glp1eu · 10 points · 1 year ago
Correcting myself upthread: the criterion I quoted was updated for this year.
comment on the compounding thing finally clicked for me and I want to write it down in c/compounding · 28 points · 1 year ago
A beyond-use date derived from published stability data means something different from one assigned by default rule. Asking which is a fair question and the answer is usually available.
comment on Sweden: excursion, and what it actually costs here in c/coldchain · 30 points · 1 year ago
Correction: that stability figure covers the lyophilised powder, not the reconstituted solution. Different claim entirely.