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226
c/glp1women·posted 16 days ago by u/step_therapy_s

[PCOS] my androgens moved before my weight did

PCOS Receipts ×7

my androgens moved before my weight did. It is the sort of thing everyone half-believes and nobody writes down.

Started logging the cycle in the same sheet as the dose. Three months later the pattern was obvious and it had been invisible before.

The same dose genuinely feels different at different points in the month for me. Took a year to notice and it was in the log the whole time.

Fertility changed faster than I expected with the weight loss. Nobody had raised it and I wish somebody had.

Sceptical readings welcome. The confident ones are the ones I distrust.

1,792 up / 1,566 down53% upvoted17 commentsid 1vmjkd14 Jul 2026

17 comments

17 in this archive, depth 4

best — the order this archive was captured in

u/blunt_coldbox_notes36 points·14 days ago

Questions about oral contraceptive absorption and gastric emptying are legitimate pharmacology questions with product-specific answers. A pharmacist can answer them properly; a board cannot.

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u/micro_bump_mick9 points·14 days ago

Have you asked a pharmacist about the absorption question specifically?

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u/greta_nilsen2 points·13 days ago

Cosigning on fertility changing with weight loss. It catches people who were not expecting it at all.

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u/ewan_zielinski0 points·14 days ago

Anything involving pregnancy, contraception efficacy or fertility planning belongs with a clinician. That is not a disclaimer, it is where the answers actually are.

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u/jonas_cardoso1 point·14 days ago

nothing on this board is a substitute for someone who knows your history

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u/ilias_kaufmann1 point·13 days ago

Small fix — insulin resistance is a feature commonly seen in PCOS, not a synonym for it.

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u/viktor_laurent42 points·14 days ago

Push back: PCOS as a diagnosis and insulin resistance as a finding are not interchangeable, and the thread is using them as one.

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u/anders_karlsen0 points·14 days ago

Push back: PCOS as a diagnosis and insulin resistance as a finding are not interchangeable, and the thread is using them as one.

viktor_laurent is right that a diagnosis and a finding are different things here.

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u/niels_roos19 points·14 days ago

cycle timing changes how the same week feels

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u/step_therapy_sOP7 points·14 days ago

Perimenopause and all of this at once, and there is essentially nothing written about the combination anywhere.

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u/anders_karlsen8 points·14 days ago

Correction: that trial did not enrol the population being discussed, so it cannot support the claim.

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u/georgi_haddad-15 points·14 days ago

Not convinced by the attribution. That pattern tracks the cycle in your own log more closely than it tracks the dose.

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u/step_therapy_sOP1 point·14 days ago

Is this a PCOS diagnosis or an insulin resistance finding?

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u/low_appetite_lisa20 points·14 days ago

That trial did not enrol the population you are asking about, so it cannot answer this.

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u/ewan_tulloch13 points·14 days ago

Brought the cycle-annotated log to an appointment and it changed the conversation completely.

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u/step_therapy_sOP0 points·14 days ago

Where in the cycle does this fall, if you are tracking it?

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u/rina_sobczak1 point·14 days ago

symptom patterns can track the cycle rather than the dose

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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