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c/glp1women·submitted 1 year ago by u/zeynep_weiss

[Results] 24 weeks on 12.5mg, full numbers, ask me anything boring

Resultsbranch of 7 comments

Six-word version is the title — 24 weeks on 12.5mg, full numbers, ask me anything boring — and the rest is context. Hard numbers: 24 weeks and 12.5mg. Anything softer than that is flagged as an impression. Questions about oral contraceptive absorption and gastric emptying are legitimate pharmacology questions with…

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7 comments, started 1 year ago
u/gentle_correctionnice about it102 points·1 year ago

The one practical change that makes this board’s hardest questions tractable: annotate your log with the cycle.

Hormonal variation affects appetite, fluid and symptom intensity in its own right. Without the annotation, a log shows a dose, a week and a set of symptoms that appear to move at random. With it, patterns that were invisible become obvious in about three months.

Members here who have done it consistently report the same thing: the same dose feels genuinely different at different points, and knowing that in advance converts a confusing fortnight into an expected one. It also makes a much better document to bring to an appointment.

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u/low_appetite_lisa25 points·1 year ago

the same dose can feel different at different points in the month

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u/jarno_karlsen9 points·1 year ago

Perimenopause and all of this at once, and there is essentially nothing written about the combination anywhere.

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u/samir_falk2 points·1 year ago

Have you asked a pharmacist about the absorption question specifically?

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u/ferran_mensah29 points·1 year ago

Perimenopausal, or is that a separate question?

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u/zeynep_weissOP18 points·1 year ago

Perimenopausal, or is that a separate question?

Adding the one thing nobody warns about — fertility can change, and quickly.

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u/dose_creep_dan13 points·1 year ago

cycle timing changes how the same week feels

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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