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c/coldchain·submitted 1 year ago by u/andres_restrepo

[Discussion] lyophilised is doing more work than we give it credit for

Discussionbranch of 6 comments

lyophilised is doing more work than we give it credit for. Not a hot take, just something I have not seen said plainly here. Put a logger in three consecutive orders. Two never went above the range at all and the third spent four hours warm on a Friday. Cost me almost nothing to stop wondering. A transit temperature…

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6 comments, started 1 year ago
u/coldchain_karencold chain229 points·1 year ago·edited

I would not freeze it in solution. That is a different failure mode and a worse one.

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u/andres_restrepoOP165 points·1 year ago·edited

ask which lines are held in regional stock before you order in July

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u/nayeli_iyer211 points·1 year ago

write the reconstitution date on the vial

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u/milan_mensah165 points·1 year ago

write the reconstitution date on the vial

Agreed, and a logger costs less than the vial you are worrying about.

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u/britt_okwuosa115 points·1 year ago

Wrote the reconstitution date on the vial for the first time last year. Have never once since wondered how old a solution is.

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[removed]158 points·1 year ago

[removed by moderator]

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Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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