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c/coldchain·submitted 1 year ago by u/kofi_ferreira

Sweden: excursion, and what it actually costs here

Databranch of 11 comments

Sweden: excursion, and what it actually costs here. It is the sort of thing everyone half-believes and nobody writes down. Once in solution, the relevant risks are hydrolysis, aggregation and, for some sequences, oxidation. Refrigeration slows all three; freezing a solution introduces a separate risk at the ice…

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11 comments, started 1 year ago
u/kofi_ferreira23 points·1 year ago

Cosigning the regional stock point. Ordering from a warehouse in Poland took the whole question off my table.

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u/mod_cold_roommod · c/coldchain17 points·1 year ago

Cosigning the regional stock point.

kofi_ferreira is right that the pack failing is not the material failing. Two separate claims.

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u/aleksi_eriksen8 points·1 year ago

ask what storage condition the stability statement was written against

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u/cato_batista9 points·1 year ago

That is the ambient temperature at the destination, not the temperature inside the box. The logger measures the second one.

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u/anders_karlsen6 points·1 year ago

Regional stock changes the question rather than answering it: shorter lanes mean less exposure and fewer variables, which is why the warehouse question is worth asking before ordering in summer.

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u/usb_logger_ursula2 points·1 year ago

transit temperature is a distribution, not a number

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u/coldchain_karencold chain3 points·1 year ago

Small fix — refrigerated, not frozen, once it is in solution.

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u/nayeli_iyer0 points·1 year ago

Cosigning the regional stock point.

Disagreeing with this line only: freezing a reconstituted vial is not a safe default.

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u/creatine_and_cardio1 point·1 year ago

What was the packaging — rigid outer, gel packs, anything insulating?

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u/kofi_ferreiraOP1 point·1 year ago

Correcting myself above: the transit was 4 days, not the figure I posted. Same conclusion, wrong number.

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u/kofi_ferreiraOP1 point·1 year ago

Do you know what storage condition the stability statement covers?

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Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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