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u/amylin_amy

Cagrilintide is the most underrated molecule in this space and I will die on that hill.

long-standing contributor · amylin · joined 30 Oct 2024

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Comments — page 3 of 3

comment on someone explain satiety to me like I have not read a paper in years in c/cagrilintide · 1 points · 1 year ago

Standing reminder: nothing here is approved standalone, research material is not for human use, and no dosing schedules for other members.

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comment on am I the only one who found sarcopenia harder than the injections in c/glp1muscle · 447 points · 1 year ago

Strength retention is an imperfect but free longitudinal proxy: it is affected by neural factors and by being in a deficit, so it tracks tissue change loosely rather than exactly.

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comment on [Lab] split one vial across VendorInvestigate and PeptideMeter — 97.2% and 96.8% in c/coa · 138 points · 1 year ago

area% is not mass%, and the difference is the whole game

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comment on [Results] 47 weeks on 0.5mg, full numbers, ask me anything boring in c/glp1muscle · 15 points · 2 years ago

Nothing here is a training or nutrition prescription. Targets and programmes are matters for somebody who knows your history and your training background.

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comment on [Question] purity — what am I missing here in c/coa · 31 points · 2 years ago

That is the catalogue certificate rather than the batch-specific one. Same layout, completely different status.

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comment on [Question] purity — what am I missing here in c/coa · 55 points · 2 years ago

What does the method line actually say? Not the technique — the column and the gradient.

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comment on [Question] purity — what am I missing here in c/coa · 303 points · 2 years ago

post the whole document, not the headline number

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comment on [Meta] the purity rule is doing its job and people should stop complaining in c/coa · 1 points · 2 years ago

Correcting myself upthread: I said the date was missing and it is on the second page, which I had not scrolled to.

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comment on week 17 check-in — 4kg down, fatigue manageable, one thing confusing me in c/cagrilintide · 612 points · 2 years ago

Retitled to distinguish the combination arm from the monotherapy arm, which the original ran together.

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comment on [Discussion] the related substances advice in here is 3 years out of date in c/coa · 889 points · 2 years ago

The PDF creation date being later than the analysis date is usually a re-issue or a re-export. It is worth one question and it is not evidence of anything on its own.

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comment on [Discussion] can we stop arguing about batch until somebody posts a number in c/coa · 99 points · 2 years ago

Correction: that is net peptide content, not purity. Different number, different meaning, and the document says so if you read the row label.

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comment on [Vendor] GL Biochem vs GGPeps on the same compound, same month — both cleared 97.5% in c/coa · 142 points · 2 years ago

Right, and net peptide content is where the counterion and the water go. Both numbers can be honest and very different.

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comment on three years of purity threads, summarised so you do not have to read them in c/coa · 5 points · 2 years ago

a total of 0.4% tells you less than four named impurities adding to 0.6%

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